inflammation is modulated by nut

2021/05/21

As inflammation is modulated by nutrition, it comes as no surprise that the impact of diet on the incidence and severity of the disease as well as on treatment response has been a matter of extensive research [13]. Jeong E.A., Jeon B.T., Shin H.J., Kim N., Lee D.H., Kim H.J., Kang S.S., Cho G.J., Choi W.S., Roh G.S. Furthermore, curcumin may enhance the secretion of anti-inflammatory cytokines such as IL-10 [240]. Based on this data, ketogenic diet is a promising prospect in psoriasis management, but large studies are needed for safe conclusions. A case-control study with 373 patients by Wolk et al. FOIA Hsu S., Dickinson D., Borke J., Walsh D.S., Wood J., Qin H., Winger J., Pearl H., Schuster G., Bollag W.B. Caputo V., Strafella C., Termine A., Dattola A., Mazzilli S., Lanna C., Cosio T., Campione E., Novelli G., Giardina E., et al.

Meng Z., Yan C., Deng Q., Gao D.F., Niu X.L. A diet enriched with 1% blueberry reduced aortic atherosclerotic lesions area in ApoE/ mice, with a concomitant increase in the antioxidant activity of superoxide dismutase (SOD) 1, SOD2 and GRx (enzymes which catalyze the dismutation of the superoxide radical) and reduced lipid peroxidation [64]. Stratigou T., Dalamaga M., Antonakos G., Marinou I., Vogiatzakis E., Christodoulatos G.S., Karampela I., Papavassiliou A.G. Hyperirisinemia is independently associated with subclinical hypothyroidism: Correlations with cardiometabolic biomarkers and risk factors. North C.J., Venter C.S., Jerling J.C. The role of fish oil in psoriasis. Deng Y.H., Alex D., Huang H.Q., Wang N., Yu N., Wang Y.T., Leung G.P., Lee S.M. Plasma lycopene is associated with pizza and pasta consumption in middle-aged and older african american and white adults in the southeastern USA in a cross-sectional study. Mediterranean Diet Foundation Expert Group Mediterranean diet pyramid today. Esposito K., Di Palo C., Maiorino M.I., Petrizzo M., Bellastella G., Siniscalchi I., Giugliano D. Long-term effect of mediterranean-style diet and calorie restriction on biomarkers of longevity and oxidative stress in overweight men. Clark C.C.T., Taghizadeh M., Nahavandi M., Jafarnejad S. E_cacy of -3 supplementation in patients with psoriasis: A meta-analysis of randomized controlled trials.

Markova M., Pivovarova O., Hornemann S., Sucher S., Frahnow T., Wegner K., Machann J., Petzke K.J., Hierholzer J., Lichtinghagen R., et al. In a subgroup analysis, higher dosages of >1800 mg/day and <8 weeks in duration were associated with more beneficial outcomes [222]. A randomized, double-blind, placebo-controlled study to evaluate the effect of fish oil and topical corticosteroid therapy in psoriasis. Bardazzi F., Balestri R., Baldi E., Antonucci A., De Tommaso S., Patrizi A. Results demonstrated that turmeric tonic significantly improved erythema, scaling and induration of lesions compared to controls [242]. on 244 healthy women, a strong positive association between a high dietary glycemic load (GL) and high-sensitive CRP (hsCRP) was demonstrated [44], and similar were the results in a study on 511 elderly subjects, where, after 1 year of follow-up, a high-glycemic index (GI) or high-GL diet led to an increase in IL-6 and TNF- levels, along with a concomitant decrease in leptin and adiponectin levels [45]. Improvement in a patient with pustular psoriasis.

Gluten-free diets are highly recommended in patients with seropositivity for celiac disease; on the other hand, high-quality evidence for other strategies, such as ketogenic and Mediterranean diets or supplements are lacking, but they seem to have a promising potential. In an RCT including 28 patients with stable chronic psoriasis, Bittiner et al. Research data regarding the effect of n-3 polyunsaturated fatty acids on the treatment of psoriasis are inconsistent.

Bahraini P., Rajabi M., Mansouri P., Sarafian G., Chalangari R., Azizian Z. Turmeric tonic as a treatment in scalp psoriasis: A randomized placebo-control clinical trial.

It becomes evident, therefore, that patients with psoriasis should be encouraged to attempt healthy lifestyle changes in order to maintain normal weight. Chambers J.C., Ueland P.M., Obeid O.A., Wrigley J., Refsum H., Kooner J.S. Yan Y., Jiang W., Spinetti T., Tardivel A., Castillo R., Bourquin C., Guarda G., Tian Z., Tschopp J., Zhou R. Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation. 1Rheumatology and Clinical Immunology Unit, Fourth Department of Internal Medicine, Attikon Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece; moc.liamg@staklep, 2Second Department of Internal Medicine, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece; moc.liamtoh@ht-roknam (E.K. National Library of Medicine Omega-6 FAs include linoleic acid (LA), mainly found in meat, and arachidonic acid (ARA), found in poultry and eggs [21]. Serino A., Salazar G. Protective Role of Polyphenols against Vascular Inflammation, Aging and Cardiovascular Disease. Rajkumar H., Mahmood N., Kumar M., Varikuti S.R., Challa H.R., Myakala S.P. Wong B.W., Meredith A., Lin D., McManus B.M. Ruedemann R., Jr. Moreover, plasma EPA levels increased in patients with oily fish intake [211]. Evidence from the Psocare project. Barrea L., Megna M., Cacciapuoti S., Frias-Toral E., Fabbrocini G., Savastano S., Colao A., Muscogiuri G. Very low-calorie ketogenic diet (VLCKD) in patients with psoriasis and obesity: An update for dermatologists and nutritionists. The intervention consisted of a 4-week VLCKD (<500 Kcal/d; 1.2 g of protein/Kg of ideal body weight/d) and a 6-week hypocaloric, low glycemic index, Mediterranean-like diet. Jaudszus A., Gruen M., Watzl B., Ness C., Roth A., Lochner A., Barz D., Gabriel H., Rothe M., Jahreis G. Evaluation of suppressive and pro-resolving effects of EPA and DHA in human primary monocytes and T-helper cells.

Miao X., Wang Y., Sun J., Sun W., Tan Y., Cai L., Zheng Y., Su G., Liu Q., Wang Y. Zinc protects against diabetes-induced pathogenic changes in the aorta: Roles of metallothionein and nuclear factor (erythroid-derived 2)-like 2. Bach-Faig A., Berry E.M., Lairon D., Reguant J., Trichopoulou A., Dernini S., Medina F.X., Battino M., Belahsen R., Miranda G., et al.

Snekvik I., Smith C.H., Nilsen T.I.L., Langan S.M., Modalsli E.H., Romundstad P.R., Saunes M. Obesity, Waist Circumference, Weight Change, and Risk of Incident Psoriasis: Prospective Data from the HUNT Study. Finally, regarding the B-complex vitamins, a high B6 intake was reversely associated with plasma CRP [115]. Studies by Michalsson et al. Chang H.K., Hou W.S. However, after 12 weeks, no significant differences between the two treatment regimens were demonstrated [208]. Siddiqui M.A., Al-Khawajah M.M. The classic ketogenic diet, very-low-carbohydrate ketogenic diet, Atkins diet, high-fat ketogenic diet and very low-calorie ketogenic diet (VLCKD) are different forms of KD. Crosstalk between skin inflammation and adipose tissue derived products: Pathogenic evidence linking psoriasis to increased adiposity. Effects of weight loss and long-term weight maintenance with diets varying in protein and glycemic index on cardiovascular risk factors: The diet, obesity, and genes (DiOGenes) study: A randomized, controlled trial. Wells J., Swaminathan A., Paseka J., Hanson C. Efficacy and Safety of a Ketogenic Diet in Children and Adolescents with Refractory Epilepsy-A Review. Furthermore, -hydroxybutyrate inhibits NLRP3 inflammasome in lipopolysaccharides (LPS)-stimulated human monocytes resulting in the reduction of IL-1 and IL-18 in a dose-dependent manner [186]. Patients with obesity and increased waist circumference have an almost two-fold risk for developing psoriasis, with relative risks being 1.87 and 1.95, respectively. Effect of Very-Low-Calorie Ketogenic Diet on Psoriasis Patients: A Nuclear Magnetic Resonance-Based Metabolomic Study. The authors report no conflict of interest. Adiponectin, another adipocytokine which is produced by white adipose tissue (WAT), exerts an anti-inflammatory action by blocking the secretion of TNF-, IL-6, IL-17 and IL-1, enhancing the secretion of IL-10 and downregulating VCAM-1 and ICAM-1 [145,146]. Del Giglio M., Gisondi P., Tessari G., Girolomoni G. Weight reduction alone may not be sufficient to maintain disease remission in obese patients with psoriasis: A randomized, investigator-blinded study. SFAs are primarily found in meat, dairy products, palm and coconut oil and processed foods which are abundant in Western-type diets and have been associated with increased inflammation in a number of studies [22,23,24,25,26].

Data about other polyphenols is scarce and is mostly based on experimental animal models. Elder J.T., Bruce A.T., Gudjonsson J.E., Johnston A., Stuart P.E., Tejasvi T., Voorhees J.J., Abecasis G.R., Nair R.P. Jensen P., Zachariae C., Christensen R., Geiker N.R., Schaadt B.K., Stender S., Hansen P.R., Astrup A., Skov L. Effect of weight loss on the severity of psoriasis: A randomized clinical study. Selenoproteins: Antioxidant selenoenzymes and beyond.

As a result, a recommendation for selenium supplementation in patients with psoriasis cannot be established. Zhang S., Liu X., Mei L., Wang H., Fang F. Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice. The The site is secure.

Neuhouser M.L., Schwarz Y., Wang C., Breymeyer K., Coronado G., Wang C.Y., Noar K., Song X., Lampe J.W. On the other hand, two RCTs showed that 1.8 g of EPA for 8 weeks or 10 capsules of fish oil three times daily for three weeks did not achieve clinical improvement compared to olive oil supplementation [218,219]. Syland E., Funk J., Rajka G., Sandberg M., Thune P., Rustad L., Helland S., Middelfart K., Odu S., Falk E.S. Similarly, according to a casecontrol study, patients with psoriasis have lower 25-hydroxyvitamin D (25(OH)D) levels compared to the control group and are more likely to have 25(OH)D deficiency [194]. Chronic inflammation and increased oxidative stress are contributing factors to many non-communicable diseases. Castellana M., Conte E., Cignarelli A., Perrini S., Giustina A., Giovanella L., Giorgino F., Trimboli P. Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: A systematic review and meta-analysis. In vitro studies supported that Vitamin B12 regulates T-lymphocytes activation and cytokine secretion [204,205]. Psoriasis is a multifactorial disease, attributed to both genetic and environmental factors. Effect of dietary supplementation with very-long-chain n-3 fatty acids in patients with psoriasis.

Yu G., Rux A.H., Ma P., Bdeir K., Sachais B.S. A 24-week randomized controlled trial by Gisondi et al. Similarly, a more recent study by Kolchak et al. enerflex protector neuron brain trust memory primrose soulful shark cartilage puritan